Senior Member

What's the best way to license Windows and Defender for Endpoint for shared PCs used by First line workers? The goal is to avoid having to assign individual E5 license to multiple users who are gonna be using the same PC. 

Described in this article, it seems like you still will be needing E3 with DFE add-on, or E5 for all users: However, i would contact MS or your license reseller to clear it out as it's a bit unclear/undocumented.
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